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One of the fastest growing subcategories of consumer natural health products is, without a doubt, the CBD sector. In a report, Grand View Research estimated the global CBD market of consumer health in 2020 at $ 9.42 billion, with an expected annual growth rate (CAGR) of 24.6% from 2020 to 2027.

Research linking CBD to health and wellness is also a worldwide spiritual activity, the results of which will continue to inform product development opportunities. According to the Grand View Research report, CBD products are multiplying like oils; tincture; concentrate; capsule; topical solutions such as lotions, salts and lip balms; as well as edible foods that include coffee, chewing gum / cakes, chocolate and bakery products. The firm noted, “Various industries such as pharmaceuticals, personal care and cosmetics, food nutrients and foods and beverages are developing CBD-derived products for health and wellness purposes.”

Researchers have identified more than 110 cannabinoids and 120 terpenes, but the authors of one study claimed that the enzymatic reaction between a resorcinol and an isoprenoid group in plants could result in nearly 150 phytocannabinoids.1

Carl Germano, CDN, a board-certified clinical nutritionist and vice president for Verdant Oasis, said emerging science that sheds light on the importance of the endocannabinoid system (ECS) and the role of hemp phytocannabinoids (including CBD) in supporting ECS ​​”will certainly dominate “food and medicine for decades to come. However, he stated, focusing only on cannabidiol as one of more than 100 phytocannabinoids “denies the synergy of all family members contributing to significant clinical benefits”.

Work, mostly in vitro and animal, continues to investigate how CBD and its phytocannabinoid siblings affect specific areas of human (and pet) health.

According to Germano, evidence is being gathered on the positive impact of phytocannabinoids, including CBD, on the musculoskeletal system. In ECS, cannabinoid receptors CB1 and CB2 are somewhat commonly present in bone and have been found to help regulate bone maintenance.2

When it comes to the exercise category, although protein and caffeine have prevailed, the role of ECS in sports performance and recovery has begun to become “one of the most important stories in sports nutrition,” Germano asserted. A recent review explored various physiological and psychological effects of CBD that may be relevant to competitive sports and exercise, despite the lack of direct human studies.3

The role of CBD in upper respiratory health is being investigated, and several in vitro studies have uncovered strong evidence to develop human clinical trials.

Beyond that, a review analyzing case reports, case series, and randomized controlled trials (RCTs) using CBD capsules or sublingual sprays either alone or in conjunction with other therapies in humans concluded that CBD (in doses varies from 6 mg to 400 mg) has a “Promising Role” in anxiety management.4

Furthermore, Jeanette Jacknin, MD, CEO of Dr. Jacknin’s Skincare LLC and author of “Smart Medicine for Your Skin,” claimed, “The research is very compelling that CBD of the day and other cannabinoids can help with acne.5.6 eczema7 and wounds.8

This article is just a sampling of a longer article with a lot more research and market data. To read it in its entirety – along with a host of additional articles in the niche – check out the CBD digital magazine.

References

1 Hanuš LO etj. “Phytocannabinoids: a Unified Critical Inventory.” Nat Prod Rep. 2016; 33: 1357-1392.

2 Chapter I, Zimmer A, Melamed E. “Cannabinoids and the Skeleton: From Marijuana to Changing Bone Loss.” Ann Med 2009; 41 (8): 560-567.

3 McCartney D et al. “Cannabidiol and Sports Performance: A Narrative Review of Relevant Evidence and Recommendations for Future Research. ” Sport Med Open. 2020; 6 (1): 27

4 Skelley JW. “Cannabidiol Use in Anxiety and Anxiety Related Disorders.” J Am Pharm Assoc. 2020; 60 (1): 253-261.

5 Olah A et al. “Cannabidiol exerts sebostatic and anti-inflammatory effects on human sebocytes.” J Clin Invest. 2014; 124 (9): 3713-3724.

6 Spleman L et al. “Safety of local cannabidiol (CBD) for the treatment of acne.” J Invest Dermatol. 2018; 138 (5): S180.

7 Petrosino S et al. “Anti-inflammatory properties of cannabidiol, a non-psychotropic cannabinoid, in allergic contact dermatitis.” J Pharmacol Exp Ther. 2018; 365 (3): 652-663.

8 Sangiovanni E et al. “Cannabis sativa L. Cannabidiol Extract Inhibits In Vitro Mediators of Skin Inflammation and Wound Injury“Phytotherapy Res. 2019; 33 (8): 2083-2093

Lisa Schofield is a veteran writer and editor who began interviewing rock stars for national music magazines. She now writes and edits content for B2B media and suppliers in the natural health products industry. She has served as editor for Vitamin Retailer and Nutrition Industry Executive, and before that as associate editor for Whole Foods.